• Assess type, location, and intensity of pain before and 2-3 hr (peak) after administration.
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• Monitor patient for seizures. May occur within recommended dose range. Risk increased with higher doses and inpatients taking antidepressants (SSRIs, tricyclics, or Mao inhibitors), opioid analgesics, or other durgs that decrese the seizure threshold.
• Overdose may cause respiratory depression and seizures. Naloxone (Narcan) may reverse some, but not all, of the symptoms of overdose. Treatment should be symptomatic and supportive. Maintain adequate respiratory exchange.
• Encourage patient to cough and breathe deeply every 2 hr to prevent atelactasis and pneumonia.
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